Though almost entirely mountainous, or at least very hilly, West Virginia is spectacularly diverse. Mountain ranges of varied character and settlement patterns of varied periods, and peoples have combined to create a strongly regionalized geography. These twelve West Virginia regions taking into account geography and culture. Boundaries may overlap, and subdivisions exist within each.
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- Allegheny Highlands Region
- Bluestone Region
- Eastern Panhandle Region
- Greenbrier Valley Region
- Hatfield & McCoy Region
- Heartland Region
- Metro Valley Region
- Mid-Ohio Valley Region
- Monongahela Valley Region
- New River Gorge Region
- Northern Panhandle Region
- Potomac Branches Region
