
Saint Marys, West Virginia

Saint Marys is one of the few remaining towns in the U.S. where trains share a street with automotive traffic.
Saint Marys, WV (West Virginia), the county seat of Pleasants County, was chartered in 1815 and named in 1859 by its founder, Alexander H. Creel, in honor of Mary, the mother of Jesus.
According to Creel, Mary appeared to him one night as the steamer upon which he was traveling passed the point on the Ohio River where he later established the town. The Cain House, which he built as a riverside inn and tavern, is listed on the National Register of Historic Places.

At Saint Mary’s Marina, a fish statue raised to angler and school principal Oran “Bull” Farren testifies to the community’s attachment to the river.
Train tracks run down the middle of 2nd Street in the town, and freight trains running through the middle of downtown are a common sight. It is one of the few remaining towns in the U.S. where freight trains share city streets with automotive traffic.
The primary sources of employment are the healthcare and manufacturing sectors, though remote-work employment is quickly increasing. The city’s water recreation is attracting new residents. The population was 1,847 at the 2020 census.
Lodging near Saint Marys, West Virginia
Parks & Recreation
Saint Marys and Pleasants County are renowned for their water recreation opportunities. The city is situated at the mouth of Middle Island Creek below Middle Island, the only island in the Ohio River Islands National Wildlife Refuge accessible by motor vehicle. A series of trails connects wildlife observation areas on the island.
Saint Marys operates a park and marina for small watercraft on “The Thoroughfare,” a waterway formed by the junction of Middle Island Creek and the Ohio River at Middle Island. Middle Island Creek and the waterway around the island are designated state water trails designed to accommodate kayaking.
Location
Saint Marys is located on highways WV-2 and WV-16 approximately three miles east of Belmont, West Virginia, 14 miles northwest of Ellenboro, West Virginia, 17 miles southwest of Sistersville, West Virginia, 20 miles east of Williamstown, West Virginia, and 15 miles northeast of the I-77 expressway at Parkersburg, West Virginia.
Map of Saint Marys, West Virginia
[mappress mapid=”234″]
Regional Information
Saint Marys is located in the Mid-Ohio Valley Region in northwestern West Virginia. The City of Saint Marys provides further information.

Recent Articles
Inside Appalachian Escapes: Themed rentals, escape rooms, and a love letter to West Virginia
FAYETTEVILLE, W.Va. — What began as a search for an affordable retirement option has turned into one of southern West Virginia’s most imaginative...
West Virginia bottler wins silver award at international water competition
BERKELEY SPRINGS, W.Va. — Le Sage Natural Water, of Lesage, has been awarded a silver medal for its purified water at the 36th annual Berkeley...
West Virginia uniquely prepared to dominate 21st-century outdoor economy
CHARLESTON, W.Va. — West Virginia is uniquely prepared to dominate in the 21st-century outdoor economy of the U.S., thanks to its unmatched...
Flood risk outpaces warnings, advocates say, as W.Va. considers changes to resiliency fund
CHARLESTON, W.Va. — As the W.Va. House of Delegates considers changes to Senate Bill 390, the West Virginia Rivers Coalition warns that the state...
We asked AI how its own data centers could pollute West Virginia. Here’s what it had to say
(The following article was generated partly by ChatGPT in response to a prompt about how data centers pollute. As ChatGPT is powered by data...
Inaugural W.Va. Outdoor Economy Summit to unite leaders around $2.1 billion growth
CHARLESTON, W.Va. — West Virginia’s outdoors are more than a scenic backdrop. They’re a strategic economic asset. That message will take...
West Virginia State Parks Foundation launches online merchandise store
HURRICANE, W.Va. — The West Virginia State Parks Foundation has launched an official online merchandise store, offering supporters a new way to...
West Virginia Travel Safety: What it means for residents and visitors in 2026
CHARLESTON, W.Va. — Travel safety in West Virginia is shaped less by headline-grabbing crime and more by geography, weather, and the realities of...
Did Abraham Lincoln and Jefferson Davis secretly meet in West Virginia?
PHILIPPI, W.Va. — Did Abraham Lincoln and Jefferson Davis secretly meet in what is now West Virginia just days after the first land battle of the...
Study finds WVU and its health system account for 17% of West Virginia’s economy
MORGANTOWN, W.Va. — West Virginia University and the WVU Health System together generate $14.3 billion in annual economic impact in West Virginia,...



















